CYP2C19 Testing for Clopidogrel Response

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CYP2C19 Testing for Clopidogrel Response

What Is Clopidogrel?

Clopidogrel (brand name: Plavix®) is a drug given to people to help protect them from a future heart attack or stroke. Heart attacks and strokes happen when a clot (or block) forms in a blood vessel that carries blood to the heart muscle or brain. When the blood flow is cut off, the heart muscle or brain tissue is damaged. These blocks are sometimes caused by platelets clumping together. Platelets are special cells in the body that stop bleeding when there is a cut or other injury. If the platelets clump together inside a blood vessel, it can cause a clot where one is not supposed to be.

Clopidogrel is an antiplatelet drug that works by keeping platelets from sticking together. It lowers the risk of new clots forming in blood vessels.

Clopidogrel may be prescribed for:

  • People who have had a recent heart attack, stroke, heart-related chest pain, or a stent placed in a blood vessel
  • People with acute coronary syndrome (ACS), a diagnosis that includes heart-related chest pain (unstable angina) and heart attack
  • People with poor circulation of the legs (peripheral artery disease, or PAD).
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